Mainz 05 vs Fiorentina: prediction & betting odds 6 November 2025

The Matchday 3 clash in the 2025/26 UEFA Europa Conference League between Mainz (Germany) and Fiorentina (Italy) will take place on November 6 at the Mewa Arena. Mainz vs. Fiorentina: prediction and betting odds, statistics.

Mainz

In the previous round, Bo Henriksen's side defeated Zrinjski at home (1-0). As a result, Mainz extended their winning streak in European competitions to three matches. Additionally, the team managed to keep a clean sheet for the fourth time in their last six European outings. It is also worth noting that the club has scored in 13 of their last 14 European matches. The Germans are in 6th place in the group stage standings with six points.

  • The team has not lost in their last seven home matches in European competitions (4 wins, 3 draws).
  • The club has not conceded more than one goal in their last seven home games in European competitions.
  • Mainz has scored exactly 1 or 2 goals in 6 of their last 7 home matches in European club tournaments.

Predicted lineup for Mainz (3-4-3)

Robin Zentner – Andreas Hanche-Olsen, Silvan Widmer, Kacper Potulski – Dominik Kohr, Kaishu Sano, Lennard Maloney, Sota Kawasaki – Ben Bobzien, Nelson Weiper, William Boving.

Defender Anthony Caci will miss the match due to injury.

Fiorentina

In the last round, the Italians comfortably defeated Rapid away (3-0). As a result, Fiorentina secured their fifth consecutive win in the Europa Conference League, marking the club's longest streak in this European competition over the past three seasons. Furthermore, the team managed to keep a clean sheet for only the third time in their last ten ECL matches. Fiorentina, along with Cypriot side AEK, tops the group stage standings with identical records of goals scored and conceded, both having six points (5:0).

  • The club has not lost in 12 of their last 15 away matches in the Europa Conference League (6 wins, 6 draws).
  • At least three goals have been scored in 7 of their last 8 away matches in this European competition.
  • The Italians have scored exactly 1 or 2 times in 5 of their last 7 away matches in the ECL.

Predicted lineup for Fiorentina (3-5-2)

David De Gea – Pablo Mari, Pietro Comuzzo, Mattia Viti – Fabiano Parisi, Cher Ndour, Hans Nicolussi Caviglia, Nicolo Fagioli, Niccolo Fortini – Roberto Piccoli, Edin Dzeko.

Defenders Robin Gosens and Tariq Lamptey, as well as forward Christian Kouame, will not play due to injuries. Notably, the club dismissed head coach Stefano Pioli before this match, and Daniele Galloppa will take over his duties.

Referee

Lawrence Visser (Belgium)

Matches – 13 (International matches, 2024/25–2025/26);

Yellow cards shown (including second yellows) – 78;

Average yellow cards per match – 6;

Red cards shown – 6;

Average fouls per match – 25;

Penalties – 23%.

Match Prediction: Mainz vs. Fiorentina

At home, Mainz tends to play aggressively upfront, and despite lacking extensive experience in European competitions, they consistently find the net. In their last seven home matches in European competitions, the team has not left the pitch without scoring. However, the club cannot boast very high scoring; in six of these matches, the Germans scored exactly 1 or 2 goals.

Fiorentina's away performances have been mixed, but the team is certainly not satisfied with their defensive play. In their last nine away matches in the Europa Conference League, the Italians have only managed to keep a clean sheet twice. Nevertheless, the club has not suffered any major defensive collapses, and in six matches with goals conceded during this period, Fiorentina did not allow their opponents to score more than two goals.

I believe the hosts will score, but not excessively. My prediction: Exact number of Mainz goals: 1-2

Betting tips 6 November 2025

Mainz 05 and ACF Fiorentina are struggling in their domestic leagues but are unbeaten in the UEFA Europa Conference League. The German side edged out Omonia Nicosia and Zrinjski Mostar, while the Italians swept aside Sigma Olomouc and Rapid Wien. Both teams have yet to concede in the tournament.

In the Bundesliga, Mainz have won only once in nine rounds and sit in the relegation zone. The defence remains the same as a year ago, and without Jonathan Burkardt the attack wastes xG. The hosts create chances but average one goal per match. In the UEFA Europa Conference League, they won 1:0 against Omonia Nicosia and Zrinjski Mostar, generating 4.81 xG across those two matches. In the Bundesliga, Mainz have conceded 17 goals, and their solidity in Europe is down to the opponents’ weak attacking play. Zrinjski Mostar played with ten men, and Omonia Nicosia produced 0.24 xG.

In Serie A, Fiorentina have not won in ten rounds and are bottom of the standings. The dismissal of Stefano Pioli is a logical outcome of the worst start in the club’s history. However, in the UEFA Europa Conference League they play with freedom: 2:0 away to Sigma Olomouc, 3:0 against SK Rapid Wien. Cher Ndour, who is kept on the bench in the league, already has 2+1, and David de Gea has kept two clean sheets. The visitors play pragmatic football and across 14 matches in all competitions this season have gone over 3.5 goals only three times.

Mainz will battle, but without Jonathan Burkardt and with poor finishing they are unlikely to contain Fiorentina. The departure of Stefano Pioli should lift the Italian club, and Cher Ndour together with Roberto Piccoli can decide it away from home. The visitors should avoid defeat, and the match is likely to feature few goals.

Betting prediction
Fiorentina to win or draw + Under 3.5
Cf
Odds
107/100
Bet now

Mainz 05 vs Fiorentina Odds

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Team lineups

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Bo Bjørnholt Henriksen
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Line-up
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gk. 0 0
Danny da Costa
df. 0 0
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df. 0 0
Phillipp Mwene
df. 0 0
Dominik Kohr
mf. 0 0
Lennard Maloney
mf. 0 0
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mf. 0 0
Paul Nebel
mf. 0 0
Sota Kawasaki
mf. 0 0
Armindo Sieb
fw. 0 0
Nelson Felix Patrick Weiper
fw. 0 0
Fiorentina

Stefano Pioli
coach
Player Matches Goals
Line-up
Tommaso Martinelli
gk. 0 0
Domilson Cordeiro dos Santos
df. 0 0
Luca Ranieri
df. 0 0
Marin Pongračić
df. 0 0
Niccolò Fortini
df. 0 0
Pablo Marí
df. 0 0
Cher Ndour
mf. 0 0
Hans Nicolussi Caviglia
mf. 0 0
Jacopo Fazzini
mf. 0 0
Simon Sohm
mf. 0 0
Roberto Piccoli
fw. 0 0

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Andy H
Andy H
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