Lille vs Lyon: prediction & betting odds 28 September 2025

The Matchday 6 clash in Ligue 1 between Lille and Lyon will take place on September 28 at the Pierre Mauroy Stadium in Villeneuve-d'Ascq. Lille vs. Lyon: prediction and betting odds, statistics.

Lille

Until last weekend, Bruno Genesio's side was one of two teams unbeaten in the new Ligue 1 season. However, in their last outing, Lille suffered a heavy defeat to Lens, ending their five-match unbeaten run in the league (4 wins, 1 draw). Importantly, the team has slipped significantly in the league standings, dropping from 2nd to 5th place. Yet, they are still just two points behind the leader.

  • At least 2 goals have been scored in 11 of Lille's last 12 league matches.
  • The team's home scoring streak in Ligue 1 stands at 44 games.
  • Bruno Genesio's side has conceded in 7 of their last 8 games in this tournament.

Predicted lineup for Lille (4-2-3-1)

Berke Ozer – Romain Perraud, Nathan Ngoy, Chancel Mbemba, Aissa Mandi – Nabil Bentaleb, Ayoub Bouaddi – Felix Correia, Hakon Haraldsson, Matias Fernandez Pardo – Olivier Giroud.

Key defenders Alessandro and Thomas Meunier are unavailable due to injuries. Midfielder Benjamin Andre and defender Romain Perraud may also miss the game for the same reason.

Lyon

In the first 5 rounds of the championship, the club suffered only 1 defeat, losing to Rennes after the international break. Following that setback, Lyon defeated Angers, marking their fifth win in their last six Ligue 1 matches – all of which were clean sheets. Paulo Fonseca's men are now among four teams that have accumulated 12 points – the best record in the league. Additionally, Lyon is the most reliable club in Ligue 1, having conceded only 3 goals since the start of the season.

  • The team has scored in their last 6 matches in the French championship.
  • Lyon's uncompromising streak in this tournament has reached 20 games (13 wins, 7 losses).
  • No more than 2 goals have been scored in 5 of the club's last 7 Ligue 1 matches.

Predicted lineup for Lyon (4-2-3-1)

Dominik Greif – Ainsley Maitland-Niles, Clinton Mata, Moussa Niakate, Nicolas Tagliafico – Jales Mera, Tanner Tessmann – Malik Fofana, Adam Karabec, Corentin Tolisso – Martin Satriano.

Main midfielder Tyler Morton has served his suspension in Ligue 1.

Referee

Mathieu Vernice (France)

Matches – 17 (Ligue 1, 2024/25–2025/26);

Yellow cards shown (including second yellows) – 73;

Average yellow cards per match – 4.3;

Red cards shown – 2;

Average fouls per match – 25;

Penalties – 24%.

Match Prediction: Lille vs. Lyon

A week ago, Lille suffered their first defeat of the current Ligue 1 season, but it's important to note that this happened away from home. At home, the team traditionally transforms and has not lost in 8 consecutive league matches. The club's scoring streak at home in Ligue 1 has reached an impressive 44 matches, and only in 4 of these games did Lille fail to earn any points. At the same time, the club rarely plays to a clean sheet – as a result, both teams have scored in 14 of Lille's last 18 home league matches. Even when considering games at all stadiums, Lille has not lost in 9 of their last 11 Ligue 1 matches, and both teams have scored in 8 of their last 12 matches in this tournament.

Lyon also earns the majority of their points at home in the championship, finding it much more challenging on the road. The club has not won in 8 of their last 12 away Ligue 1 matches (1 draw, 7 losses). However, it should be noted that even in unfavorable outcomes, the team almost never ends a match without scoring a goal, resulting in both teams scoring in 9 of the 12 noted matches.

Finally, Lille has avoided defeat in 6 of their last 8 home meetings with Lyon in Ligue 1 (1 win, 6 draws), with both teams scoring in 7 of these 8 matches. Prediction – 1X and both teams to score – yes

Lille vs Lyon Odds

1X2
DOUBLE CHANCE
OVER/UNDER
BTTS
TOTAL HOME GOALS
TOTAL AWAY GOALS
Bookie1X2

Current season

Logo Lille Logo Olympique Lyonnais
3 Wins 4
1 Lost 1
1 Draws 0
2.6 GF per game 1.4
1.6 GA per game 0.6
7 Corners per game 6.4
2 Yellow cards per game 1.8

Ligue 1: previous matches in the tournament

Lille
20.09.25
Lens
Lille
L
14.09.25
Lille
Toulouse
W
30.08.25
Lorient
Lille
W
24.08.25
Lille
Monaco
W
17.08.25
Brest
Lille
D
More matches
Lyon
19.09.25
Lyon
Angers
W
14.09.25
Rennes
Lyon
L
31.08.25
Lyon
Marseille
W
23.08.25
Lyon
Metz
W
16.08.25
Lens
Lyon
W
More matches

H2H: Lille — Lyon

Ligue 1 2024-2025
05.04.25
Lyon
Lille
01.11.24
Lille
Lyon
Ligue 1 2023-2024
06.05.24
Lille
Lyon
French Cup 2023-2024
07.02.24
Lyon
Lille
Ligue 1 2023-2024
26.11.23
Lyon
Lille
Ligue 1 2022-2023
10.03.23
Lille
Lyon
French Cup 2022-2023
08.02.23
Lyon
Lille
2
:
2
4
:
2
P
Ligue 1 2022-2023
30.10.22
Lyon
Lille
Ligue 1 2021-2022
27.02.22
Lyon
Lille
12.12.21
Lille
Lyon
Ligue 1 2020-2021
25.04.21
Lyon
Lille
01.11.20
Lille
Lyon
Ligue 1 2019-2020
08.03.20
Lille
Lyon
Coupe de la Ligue French 2019-2020
21.01.20
Lyon
Lille
2
:
2
4
:
3
P
Ligue 1 2019-2020
03.12.19
Lyon
Lille
Ligue 1 2018-2019
05.05.19
Lyon
Lille
01.12.18
Lille
Lyon
Ligue 1 2017-2018
18.02.18
Lille
Lyon
29.11.17
Lyon
Lille
Ligue 1 2016-2017
28.01.17
Lyon
Lille
18.11.16
Lille
Lyon
Ligue 1 2015-2016
21.02.16
Lille
Lyon
12.09.15
Lyon
Lille
Ligue 1 2014-2015
28.02.15
Lille
Lyon
05.10.14
Lyon
Lille
Ligue 1 2013-2014
22.02.14
Lille
Lyon
0
:
0
27.09.13
Lyon
Lille
0
:
0
Ligue 1 2012-2013
09.02.13
Lyon
Lille
1
:
3
22.09.12
Lille
Lyon
1
:
1
Ligue 1 2011-2012
09.03.12
Lyon
Lille
2
:
1
Coupe de la Ligue French 2011-2012
11.01.12
Lyon
Lille
2
:
1
Ligue 1 2011-2012
22.10.11
Lille
Lyon
3
:
1
Ligue 1 2010-2011
26.02.11
Lille
Lyon
1
:
1
16.10.10
Lyon
Lille
3
:
1
Ligue 1 2009-2010
10.04.10
Lyon
Lille
1
:
1
05.12.09
Lille
Lyon
4
:
3
Ligue 1 2008-2009
06.03.09
Lille
Lyon
2
:
0
17.10.08
Lyon
Lille
2
:
2
Ligue 1 2007-2008
29.02.08
Lille
Lyon
0
:
1
22.09.07
Lyon
Lille
1
:
1
Ligue 1 2006-2007
15.02.07
Lille
Lyon
1
:
2
22.09.06
Lyon
Lille
4
:
1
Ligue 1 2005-2006
05.05.06
Lille
Lyon
4
:
0
15.12.05
Lyon
Lille
1
:
3
Ligue 1 2004-2005
22.01.05
Lille
Lyon
2
:
1
27.08.04
Lyon
Lille
1
:
0
More matches

Tables

Team Played W D L Goals Points Form
1
Marseille
6 4 0 2 12:5 12
2
Monaco
5 4 0 1 13:7 12
3
PSG
5 4 0 1 10:4 12
4
Lyon
5 4 0 1 7:3 12
5
Strasbourg
6 4 0 2 9:7 12
6
Lille
5 3 1 1 13:8 10
7
Lens
5 3 0 2 8:5 9
8
Rennes
5 2 2 1 7:8 8
9
Toulouse
5 2 0 3 7:9 6
10
Auxerre
5 2 0 3 4:6 6
11
FC Paris
5 2 0 3 9:12 6
12
Nice
5 2 0 3 6:9 6
13
Angers
5 1 2 2 3:4 5
14
Brest
5 1 1 3 9:11 4
15
Le Havre
5 1 1 3 6:8 4
16
Nantes
5 1 1 3 3:5 4
17
Lorient
5 1 1 3 6:13 4
18
Metz
5 0 1 4 5:13 1
Team Played W D L Goals Points Form
1
Marseille
3 3 0 0 10:2 9
2
Monaco
3 3 0 0 11:5 9
3
Lyon
3 3 0 0 5:0 9
4
PSG
2 2 0 0 3:0 6
5
Strasbourg
3 2 0 1 3:2 6
6
Lille
2 2 0 0 3:1 6
7
Lens
3 2 0 1 6:2 6
8
Rennes
2 2 0 0 4:1 6
9
Auxerre
3 2 0 1 3:2 6
10
Nice
3 2 0 1 4:2 6
11
Angers
2 1 1 0 2:1 4
12
Brest
3 1 1 1 8:6 4
13
Le Havre
3 1 1 1 5:4 4
14
Nantes
3 1 1 1 3:3 4
15
Toulouse
2 1 0 1 5:6 3
16
FC Paris
2 1 0 1 5:5 3
17
Lorient
2 1 0 1 5:7 3
18
Metz
2 0 1 1 1:2 1
Team Played W D L Goals Points Form
1
PSG
3 2 0 1 7:4 6
2
Strasbourg
3 2 0 1 6:5 6
3
Lille
3 1 1 1 10:7 4
4
Marseille
3 1 0 2 2:3 3
5
Monaco
2 1 0 1 2:2 3
6
Lyon
2 1 0 1 2:3 3
7
Lens
2 1 0 1 2:3 3
8
Toulouse
3 1 0 2 2:3 3
9
FC Paris
3 1 0 2 4:7 3
10
Rennes
3 0 2 1 3:7 2
11
Angers
3 0 1 2 1:3 1
12
Lorient
3 0 1 2 1:6 1
13
Auxerre
2 0 0 2 1:4 0
14
Nice
2 0 0 2 2:7 0
15
Brest
2 0 0 2 1:5 0
16
Le Havre
2 0 0 2 1:4 0
17
Nantes
2 0 0 2 0:2 0
18
Metz
3 0 0 3 4:11 0

Team lineups

The line-ups will be known a few hours before kick-off
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