Sassuolo go into the match after a 2:1 Serie A win over Torino, while the visitors shocked everyone by thrashing Fiorentina 3:0 away from home in the second round of the league season. In the previous cup round, Sassuolo comfortably beat Cesena 3:0, while Frosinone defeated Juve Stabia 4:1 in the Round of 64. Can the Serie A newcomers challenge their more experienced opponents, or will the hosts confirm their status as favourites?
Sassuolo
Alberto Aquilani's side are building momentum: a convincing 2:1 win over Torino followed their 1:2 defeat to Atalanta. The Neroverdi have also looked solid in the cup — they have won three of their last four cup matches and reached the quarter-finals in 2021/22 and 2023/24. First-choice striker Andrea Pinamonti left the squad in the summer, but Sebastiano Esposito arrived from Cagliari to replace him; he can operate both as a traditional number nine and in the half-space. Armand Laurienté and Cristian Volpato have also stayed in attack, while Domenico Berardi is expected to return on the flank, which will significantly increase the pressure on the visitors' defence.
Frosinone
The visitors have made a bright start to Serie A following their return to the top flight: their 3:0 win over Fiorentina in Florence was a real sensation. The team played with discipline and took their chances, with Alessandro Raimondo scoring twice and Gabriele Bracaglia adding another goal. However, Frosinone's Coppa Italia record is modest — in more than 90% of seasons, the club are eliminated before the Round of 32, although they made a historic run to the quarter-finals in 2023/24 after thrashing Napoli 4:0 in Naples.
Sassuolo vs Frosinone Prediction
Even taking their impressive win over Fiorentina into account, Frosinone are unlikely to surprise a top opponent away from home twice in a row. Sassuolo are motivated enough and have every tool needed to win in normal time.

