Atalanta vs Slavia Prague: prediction & betting odds 22 October 2025

Atalanta bounced back from their setback in Paris with a strong win over a dangerous Club Brugge side. Next up, they face Slavia Prague, who were thoroughly outclassed by Inter Milan in their previous Champions League outing.

Under Ivan Jurić, Atalanta continue to build on the attacking identity established by Gian Piero Gasperini — vibrant football coupled with confidence and structure. In Serie A, the Bergamo side remain unbeaten and trail leaders AC Milan by just five points. At home, they have yet to lose in any competition this season. Their Champions League campaign started unevenly, but the hard-fought 2:1 victory over Club Brugge — sealed by Mario Pašalić’s decisive penalty in the 87th minute — restored belief. Atalanta have shown a more pragmatic approach this year, with only one of their nine matches producing over 4.5 goals.

Jindřich Trpišovský’s Slavia Prague, meanwhile, are struggling to make an impact in Europe despite their manager’s experience. A 2:2 draw with Bodø/Glimt and a 0:3 defeat to Inter Milan have left them with just one point from two games. Their away form in European competition is worrying — four straight losses — and a lengthy injury list (Jindřich Staněk, David Douděra, Igoh Ogbu) plus several unregistered players (Ondřej Zmrzlý, Emmanuel Fully, Lukáš Vorlický, Ondřej Kolář) only make matters worse. Domestically, Slavia sit second in the Czech league, but their compact defensive system has failed to cope with top-level opposition — conceding five goals in two Champions League matches tells its own story.

Atalanta are clear favourites at home, and Slavia lack the quality and depth to match the Italians’ tempo. Expect a professional performance from the hosts without an avalanche of goals.